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critical cleaning in pharmaceutical cleanrooms

Cleaning validation in the Pharmaceutical Industry is paramount as far as human health and safety is concerned. The increasing demand for quality products to avoid health risks, and other pharmaceutical manufacturing factors have driven the Cleanroom Technology market growth globally. Critical Cleaning Chemicals used in cleanroom cleaning emphasizes a greater degree of environmental control than any other cleaning environment. Equipment that wouldn’t withstand longer if not cleaned properly are usually critically cleaned as it primarily focuses on removing submicron particles and non-volatile residues.

Why do you need clean Pharmaceutical processing equipment?
1. Cleanliness maintains product quality.
2. It abides by the local and international standards and regulations to ensure consumer safety and avoids further legal complications.
3. It boosts worker safety by providing a clean working environment to work in.
4. It maintains your brand’s reputation in the market.

The cleaning process must be cultivated carefully to achieve the most beneficial and cost-effective results. If you are a pharmaceutical company and find yourself confused about the usage of critical cleaners then have a look at the below crucial points to be considered before you jump into the critical cleaning regime of your Cleanrooms.
1. Determine the suitable cleaning method– Among all the cleaning methods like CIP, ultrasonic, manual, immersion, automatic systems and pressure washing systems, determine what suits your requirement accurately.
2. Choose a deep cleaning detergent– The active enzymes present in the critical cleaning detergent should be compatible with the floor and should leave it clean without damaging it. Avoid harsh chemicals like acid and alkaline cleaners on delicate substances, rather rely on cleaning chemicals with a pH below 10.
3. Treat your equipment gently– Choose Lubricants for critical equipment during autoclave that will not only lubricate them but also leave behind the protective coating. For removing stains from metal surfaces, go for rust and stain remover with effective enzymes. The more you treat your equipment with care, the cleaner environment you will attain.
4. Use the right concentration of detergent– Using too much detergent is as troublesome as using too less for critical cleaning. Analyze the surface you want to clean, the soil, the temperature and determine the suitable cleaning method before you zero down on using the amount of detergent, as the strength of the cleaning solution varies from detergent to detergent.
5. Set up the length of the cleaning cycle– Increase the dwell time and consider the required temperature of the cleaning solution, the concentration of detergent, cleaning method and type of water used to achieve the most efficient cleaning regime for any application.
6. Make rinsing a habit– It is always advisable to rinse thoroughly post applying detergent on your substance. Rinsing with deionized or distilled water removes any excess detergent left behind.

While choosing the best critical cleaners for your Pharmaceutical Cleanrooms, eliminate ‘a pig in a poke’ approach to attack the cleaning challenges. Settle down for the most effective and suitable cleaning methods and make sure the entire cleaning regime has been standardized and documented according to the FDA’s cGMP regulations.

As June Enterprises owes to serve you the best, you can always feel free to seek assistance from us for all your Pharmaceutical cleaning dilemmas.

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